Epieriocalyxin A
產品名稱:Epieriocalyxin A
產品描述:
植物來源 | 天然產物 > 唇形科 > 香茶菜屬 |
結構類型 | 天然產物 > 萜類 |
產品描述 | Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future. |
體外活性 | Epieriocalyxin A (EpiA), a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. EpiA induced annexin V flipping in the cell membrane and DNA fragment. We also showed that EpiA induced the generation of ROS in cells, as well as damage of the mitochondrial membrane. Western blot results showed that both JNK and ERK1/2 activation was decreased after EpiA treatment in a dose-dependent manner. EpiA increased the expression of caspase 3 and Bax and decreased Bcl2 expression. |
分子量 | 344.4 |
分子式 | C20H24O5 |
CAS No. | 191545-24-1 |
存儲
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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