Pancreatic Polypeptide, rat acetate
作者：齊岳
發(fā)布時間：2023-06-27
09:10:47
點擊數(shù)：
產(chǎn)品名稱：Pancreatic Polypeptide, rat acetate
產(chǎn)品描述：
| 產(chǎn)品描述 | Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4. |
| 體外活性 | Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic Polypeptide, rat acetate (1 μM) does not alter proliferation in BRIN BD11 or 1.1B4 beta-cells, but reverses the decreased cell viability in BRIN BD11 cells induced by streptozotocin. Pancreatic Polypeptide, rat acetate (0.1 nM-1 μM) shows no effect on insulin secretion from isolated mouse islets, and does not affect the membrane potential and (Ca2+)i levels in BRIN BD11 cells at 1 μM[1]. |
| 體內(nèi)活性 | Pancreatic Polypeptide, rat acetate (25 nmol/kg bw, i.p.) reduces glucose-stimulated insulin concentrations but shows no effect on acute feeding behaviour in overnight fasted mice[1]. |
| 分子量 | N/A |
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